New tool fights against prescription drug abuse

Tris Pharma has unveiled a key component in the fight against opioid abuse in the US with its new drug delivery platform, NoBuse, which enables companies to deliver effective pain relief that are nearly impervious to abuse.

The delivery system is engineered to prevent abuse on a physical level without the need for additional ingredients.

It employs a technique where the drug is complexed to very fine polymeric particles and coated with a highly flexible non-breakable film resulting in particles that are extremely difficult to extract drug from-even after crushing the tablet or dissolving it in alcohol.

The company says the technology works across a range of oral dosage forms including tablets, liquid suspensions, orally disintegrating tablets, and drug strips.

It can also be used to formulate an immediate-release product with a built-in abuse deterrent.