Bench-top NMR Reader to quantify hyperpolarization

At the 2008 World Molecular Imaging Congress, Bruker BioSpin introduces HyperQuant, a bench-top NMR reader for precisely quantifying both the magnetic hyperpolarization as well as the thermal polarization of a sample.

The HyperQuant applies time-domain nuclear magnetic resonance (TD-NMR) spectroscopy, a technology similar to magnetic resonance imaging (MRI).

Magnetic hyperpolarization promises to be a useful technique with potential to boost contrast in MRI and sensitivity in solid-state NMR.

Hyperpolarization provides a means to increase the nuclear magnetic polarization by orders of magnitude compared to the thermal Boltzmann polarization.

Today, hyperpolarization can be achieved by various mechanisms, including DNP (dynamic nuclear polarization) and parahydrogen-induced polarization (PHIP).

Typically, carbon‑13 labeled samples are utilized because of their preferential NMR properties.