Applied Biosystems Introduces Real-time PCR Solution

Applied Biosystems has launched its first integrated real-time Polymerase Chain Reaction (PCR) solution for measuring residual DNA impurities from Chinese Hamster Ovary (CHO) host cells. The solution enhances the ability of biopharmaceutical companies to rapidly and accurately quantitate the impurities. The CHO cell lines are the primary medium used by biopharmaceutical companies to develop biological drugs, which are designed to treat a variety of medical conditions, including cancer, cardiovascular disease, inflammatory diseases, multiple sclerosis and viral infection.

The resDNASEQ CHO Residual DNA Quantitation and PrepSEQ Sample Preparation kits are the latest additions to the SEQ portfolio of rapid molecular methods for pharmaceutical manufacturing. The solution combines DNA isolation technology in a magnetic bead-based kit for high DNA recovery with a sensitive qPCR assay, including a genomic CHO standard for generating accurate and specific quantitation data.