Amsbio Introduces Non-Animal Recombinant Proteins for Cell Culture

Amsbio has announced a range of recombinant proteins that can substitute extracellular matrix proteins that are currently extracted from mouse sarcoma.

The Mussel Adhesive Protein based matrix (MAPTrix) ECM line of products are coating reagents with genetically incorporated bioactive peptides which mimic the extracellular matrix (ECM) activity of collagen, fibronectin, laminin, and vitronectin proteins. These bioactive peptides mimic ECM proteins and provide for cell attachment, spreading and growth. A surface coating offers an animal-free, chemically defined attachment and growth surface that provides a controlled environment for cell culture and tissue engineering applications.

Cell adhesion to the extracellular matrix is essential for the development and maintenance of cells. Cell adhesion to ECM ligands is primarily mediated by integrins. The Arg-Gly-Asp (RGD) recognition motif is present in many ECM proteins including fibronectin, laminin, and osteopontin.